Chemicals and intermediates used in pharmaceutical manufacturing and drug development.
chemXplore tracks 134 projects in pharma, of which 35 are active.
19 new construction, 15 expansion, and 1 revamp / retrofit.
Expected to start operating, per year; 2 of the active projects carry no start-up date yet.
Owners and developers: Evonik Industries AG (4), Lilly (3), Merck (3), Novo Nordisk (3), Eli Lilly and Company (2), Genentech, Inc. (2)
Investors: Eli Lilly and Company (2), Evonik Industries AG (2), Takeda (2), AGC Group (1), Clariant AG (1), European Investment Bank (1)
Contractors, licensors, and offtakers are recorded on 12 of these 35 projects For subscribers
Targeting: Orforglipron (5), Retatrutide (2), Coagulation factor IX (1), Glucagon-like peptide-1 (1), Isobutene (1), Lead-212 (1)
€15m first tranche of a €35m package to expand a Colombian plant to produce up to 250m doses annually, plus a €1.5m R&D grant for three vaccine candidates.
Tri-specific Wnt-pathway agonist showed non-inferior BCVA gains vs ranibizumab at week 52; higher rates of PDR, vitreous hemorrhage and discontinuations observed.
Passed a two-week unannounced FDA GMP inspection covering drug substance and drug product manufacturing, reinforcing U.S. commercial supply reliability.
FDA clears once‑weekly basal insulin that reduces injection frequency vs daily therapy; Phase 3 QWINT trials in >3,400 adults showed non‑inferior A1C vs glargine and degludec.
Modeling of MajesTEC‑3 trial data estimates a high cure fraction and nearly fourfold median OS benefit for teclistamab plus daratumumab FASPRO versus standard care in relapsed/refractory myeloma.
Interim analysis shows significant, clinically meaningful 24‑hour UPCR reduction at 37 weeks; blinded study continues to the eGFR endpoint at week 105.
Phase III interim data show significant proteinuria reduction at 37 weeks; drug targets liver-derived factor B via monthly subcutaneous dosing; blinded follow-up continues to week 105 eGFR.
Phase 3 trial showed rapid, sustained reduction in systemic disease activity in moderate-to-severe Sjögren's disease with manageable safety signals.
Three world-scale acetyls units in Hull mothballed, threatening nearly 4,000 skilled jobs and eliminating Europe’s last large acetyls capacity amid extreme gas-price disparity.
FDA updates PAH therapy label to include HYPERION data showing a 76% reduction in clinical worsening when added to background therapy for patients diagnosed within 12 months.
By country, the most active first.
The 8 with the most active projects, of 25 countries.