Chemical Industry News, Data & Insights

Johnson & Johnson Ends Phase 2b DUPLEX-AD Study

Key highlights
  • The Phase 2b DUPLEX-AD study evaluated JNJ-95475939 for atopic dermatitis.
  • The study was terminated early due to not meeting efficacy criteria.
  • JNJ-5939 was well tolerated during the study.

Study Overview

The Phase 2b DUPLEX-AD study, identified as 95475939ADM2001, assessed the efficacy of JNJ-95475939 (JNJ-5939) for treating moderate to severe atopic dermatitis.

Study Termination

The study was concluded early following an interim analysis, as it did not meet the predefined high-bar efficacy criteria necessary for advancing clinical development.

Tolerability

Despite the early termination, JNJ-5939 was well tolerated by participants during the study.

Commitment to Research

Johnson & Johnson remains dedicated to developing treatments for atopic dermatitis, a chronic condition affecting over 100 million people globally.