Johnson & Johnson to present neuropsychiatry data at Psych Congress 2026

Key highlights
  • Johnson & Johnson will present 24 abstracts at the Psych Congress Annual Meeting (Sept 15–19, 2026) in New Orleans.
  • Pivotal Phase 3 data for CAPLYTA (lumateperone) in acute bipolar I mania will be presented, alongside additional CAPLYTA analyses across bipolar depression and MDD.
  • Analyses of SPRAVATO (esketamine) on anhedonia and Phase 3 clinical trial data for seltorexant in MDD with insomnia symptoms will be shown.
  • A supplemental NDA for CAPLYTA with long‑term data showing reduced risk of relapse in schizophrenia has been approved by the FDA.

Conference participation

Johnson & Johnson will present 24 abstracts featuring clinical data and real‑world evidence across its neuropsychiatry portfolio at the Psych Congress Annual Meeting (September 15–19, 2026) in New Orleans.

Key clinical findings

New pivotal Phase 3 data evaluating CAPLYTA (lumateperone) in the acute treatment of manic episodes or manic episodes with mixed features associated with bipolar I disorder will be presented. Additional CAPLYTA data will cover adjunctive use in MDD across depressive symptoms, remission, patient subgroups and metabolic outcomes.

New analyses of SPRAVATO (esketamine) nasal spray will examine its impact on anhedonia, and Phase 3 clinical trial data for seltorexant will be presented for major depressive disorder with insomnia symptoms.

Real‑world evidence and long‑acting injectables

Presented real‑world studies will include CAPLYTA treatment patterns in bipolar depression (dosing and duration) and LAI studies assessing schizophrenia‑related hospitalizations in young dual‑eligible patients before LAI initiation, subsequent relapse risk, and treatment satisfaction with LAIs. The company will support educational programs, in‑booth presentations and training, including interactive PRIDE LAI visualizations and CAPLYTA schizophrenia and network meta‑analysis findings.

Regulatory and usage notes

A supplemental NDA for CAPLYTA containing long‑term data on delayed time to relapse in schizophrenia was recently approved by the U.S. FDA. SPRAVATO has been approved in more than 70 markets and administered to over 250,000 patients worldwide. The full list of presentations is available on JNJ.com.

Source: J&J

chemXplore Weekly

The week’s project milestones and project news from the chemical industry, free every Wednesday.

Free. One email a week. Unsubscribe any time.

Related articles

4 May 2026
Johnson & Johnson: CAPLYTA tops adjunctive MDD antipsychotics in network meta-analysis

Network meta-analysis of 10 trials found an adjunctive atypical antipsychotic superior on MADRS change, response, remission and CGI‑S, with no significant weight gain and favorable tolerability.

15 July 2026
Johnson & Johnson Q2 2026 results and raises 2026 outlook

Quarterly sales topped $25.3B; adjusted net earnings and EPS rose, free cash flow improved, and full-year revenue guidance was raised above $100B for the first time.

27 April 2026
Johnson & Johnson: FDA approves CAPLYTA sNDA to reduce schizophrenia relapse risk

FDA approved sNDA for CAPLYTA (lumateperone) to prevent relapse in schizophrenia. Phase 3 randomized‑withdrawal: 63% lower relapse risk (HR 0.37); 84% relapse‑free at 6 months; safety consistent.

16 January 2026
Johnson & Johnson's CAPLYTA® Shows Promise for Remission in Major Depressive Disorder

CAPLYTA® nearly doubles remission rates in major depressive disorder when used with antidepressants, showing sustained benefits over six months in clinical studies.

13 January 2026
Johnson & Johnson Presents New Depression Data at 2026 ACNP Meeting

11 abstracts on neuropsychiatry, including MDD and TRD, will be presented, highlighting clinical and preclinical research, AI tools, and novel therapeutic mechanisms.