Key highlights
- Global debut at PCHi 2026 in Hangzhou, March 18–20.
- SPHINOX Vively is a designer sphingolipid delivering retinol-like rejuvenation with improved tolerance compared with unencapsulated retinol.
- Stimulates elastin and hyaluronic acid production, increases Ceramide AP and EOP, and reduces IL-1α release.
- Biotechnology-derived, readily biodegradable, and produced using partially renewable feedstocks.
Launch and debut
Evonik launched SPHINOX® Vively, making its global debut at PCHi 2026 in Hangzhou (March 18–20).
Chemistry and intended action
SPHINOX Vively is a designer sphingolipid bioactive engineered to support skin vitality by stimulating elastin and hyaluronic acid synthesis and by increasing Ceramide AP and EOP levels to strengthen the skin barrier.
Efficacy and tolerance
Reported data indicate retinol-like rejuvenation comparable to unencapsulated retinol in stimulating elastin and hyaluronic acid, with significantly improved tolerance, reduced IL-1α release, and less barrier disruption or irritation.
Sustainability and production
The ingredient is biotechnology-derived, readily biodegradable, and produced using partially renewable feedstocks, positioning it as a performance ingredient with sustainability attributes.
