Bota Biosciences (杭州恩和生物科技有限公司), known as Bota Bio, is a Hangzhou, China-based industrial biotechnology company founded in 2019. It specializes in AI-driven biomanufacturing platforms to engineer microbial strains and enzymes for sustainable production of high-value compounds.
Leveraging technologies like the SAION AI platform—a full-stack Physical AI system integrating cognition, orchestration, and robotic lab execution—the company accelerates design-build-test-learn cycles. Its Bota Freeway™ and Biofoundry enable efficient scaling from lab to industrial production, including 4000L facilities.
Bota Bio serves sectors such as nutrition, food biopreservatives, personal care, and pharmaceuticals, partnering with firms like BASF, NHU, Syensqo, and Proya. Notable applications include bio-identical collagen fragments via vegan yeast fermentation and upcycled coffee peptides for cosmetics. The firm has raised over $100 million in Series B funding and achieved commercial milestones, transforming chemical manufacturing into bio-based processes.
Also known as 恩和生物, 恩和科技, and Enhe Technology.
A 100% human-identical recombinant Collagen III fragment made by yeast fermentation; discovered with Physical AI, it boosted collagen markers in models and improved sagging and wrinkles in four-week trials.
Two actives: a precision peptide reducing damaged collagen 41% and raising hyaluronic acid 65%; a recombinant bio‑identical Collagen III fragment that boosts Coll I/III/V and improves tone & wrinkles
