25 May 2026
Lilly's VERVE-102 single infusion durably lowers PCSK9 up to 88% and LDL-C up to 62%
Phase 1b Heart-2: single IV base-editing dose gave dose-dependent, durable PCSK9/LDL-C reductions up to 18 months in HeFH/premature CAD; well tolerated; FDA Fast Track; Phase 2 planned.